Hot Sell Pharmaceutical Intermediate Gdf-8 with Best Price- Xi'an Frazer Biotech Co., Ltd.

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Hot Sell Pharmaceutical Intermediate Gdf-8 with Best Price

FOB Price:US $20-48 / Box(es)
Min.Order:1 Box(es)
Production Capacity:100boxes
Payment Terms:L/C , T/T , D/P , PayPal , Others(Alibaba)

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Xi'an Frazer Biotech Co., Ltd.

Business Type:Trader

Country/Region:China

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HOT Rank

8/10

Product Information

Active Ingredients:Gdf-8
Chemical Formula:C129H215N33O55
Molecular Weight:3108.275
Assay:98%
Pharmacopeia:USP
Package Type:Bottle
Shelf Life:18 months
Storage:2℃-8℃
Place of Origin:China
MOQ :1box
Shipping method:Fedex, DHL, EMS

Description

Description
GDF-8 is a myokine, a protein produced and released by myocytes that acts on muscle cells' autocrine function to inhibit myogenesis: muscle cell growth and differentiation. In humans it is encoded by the MSTN gene.Myostatin is a secreted differentiation that is a member of the beta protein family.

GDF-8 is a member of the transforming (TGF-beta) superfamily that is highly expressed in skeletal muscle, and myostatin loss-of-function leads to doubling of skeletal muscle mass. Myostatin-deficient mice have been used as a model for studying muscle-bone interactions, and here we review the skeletal phenotype associated with altered myostatin signaling. It is now known that myostatin is a key regulator of mesenchymal stem cell proliferation and differentiation, and mice lacking the myostatin gene show decreased body fat and a generalized increase in bone density and strength. The increase in bone density is observed in most anatomical regions, including the limbs, spine, and jaw, and myostatin inhibitors have been observed to significantly increase bone formation. Myostatin is also expressed in the early phases of fracture healing, and myostatin deficiency leads to increased fracture callus size and strength. Together, these data suggest that myostatin has direct effects on the proliferation and differentiation of osteoprogenitor cells, and that myostatin antagonists and are likely to enhance both muscle mass and bone strength.

Application
1. Treat muscle atrophy, strengthen muscle toughness,Increase muscle number.
2. Treating malnutrition patients is an important index of the strength training athletes.
3. GDF-8 can effectively prevent the increased due to age brings the increase of adipose tissue, and reduce the occurrence of diabetes.

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